Lawrence Talbot is lured back to his family estate to investigate the savage murder of his brother by a bloodthirsty beast. There, Talbot must confront his childhood demons, his estranged father, his brother's grieving fiancee, and a suspicious Scotland Yard nspector. When Talbot is bitten by the creature, he becomes eternally cursed and soon discovers a fate far worse than death.

After the birth of Renesmee, the Cullens gather other vampire clans in order to protect the child from a false allegation that puts the family in front of the Volturi.